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Txnip Regulates the Oct4-Mediated Pluripotency Circuitry via Metabolic Changes upon Differentiation

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Researchers revealed the novel functions of mouse Txnip in cellular reprogramming and differentiation onset by involving in glucose-mediated histone acetylation and the regulation of Oct4, which was a fundamental component of the molecular circuitry underlying pluripotency.
[Cellular and Molecular Life Sciences]
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