Home Newsletters Muscle Cell News Mitolnc Controls Cardiac BCAA Metabolism and Heart Hypertrophy by Allosteric Activation of...

Mitolnc Controls Cardiac BCAA Metabolism and Heart Hypertrophy by Allosteric Activation of BCKDH

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Investigators described the function of mitolnc in cardiomyocytes, a nuclear encoded long non-coding RNA, located in mitochondria and directly interacting with the branched-chain ketoacid dehydrogenase (BCKDH) complex to increase its activity.
[Nucleic Acids Research]
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