The authors observed reduced DEAH-box helicase 9 (DHX9) protein levels in IBD patients, and mice with conditional DHX9 depletion in the intestinal epithelium exhibited an increased susceptibility to experimental colitis.
[Nature Communications]
Home Newsletters Intestinal Cell News DHX9 Maintains Epithelial Homeostasis by Restraining R-Loop-Mediated Genomic Instability in Intestinal Stem...
