NewslettersMuscle Cell News Inhibition of CDK7 Mitigates Doxorubicin Cardiotoxicity and Enhances Anticancer Efficacy By Noshin Noorjahan - April 24, 2024 0 Doxorubicin (DOX) exposure induced CDK7 activation in mouse heart and isolated cardiomyocytes. Cardiac-specific ablation of cyclin-dependent kinase 7 (CDK7) attenuated DOX-induced cardiac dysfunction and fibrosis. [Cardiovascular Research] Abstract