Placental Circulating T Cells: A Novel, Allogeneic CAR-T Cell Platform with Preserved T Cell Stemness, More Favorable Cytokine Profile, and Durable Efficacy Compared to Adult PBMC-Derived CAR-T

Investigators compared CAR-T cells generated from healthy adult peripheral blood T cells versus placental circulating T (P-T) cells. CAR-T cells from healthy adult peripheral blood mononuclear cells and P-T cells were generated using the same protocol.