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METTL3-Mediated Deficiency of lncRNA HAR1A Drives Non-Small Cell Lung Cancer Growth and Metastasis by Promoting ANXA2 Stabilization

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Researchers identified the oncogenic protein annexin 2 (ANXA2) as a potential interacting patterner of highly accelerated region 1A (HAR1A). HAR1A overexpression enhanced ANXA2 ubiquitination and accelerated its degradation via the ubiquitin–proteasome pathway.
[Cell Death Discovery]
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