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Impact of the Thyroid Hormone T3 and its Nuclear Receptor TRα1 on Colon Cancer Stem Cell Phenotypes and Response to Chemotherapies

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Researchers used an established spheroid model generated from the human colon adenocarcinoma cell line Caco2 to study the effects of T3 and TRα1 on spheroid formation, growth, and response to conventional chemotherapies.
[Cell Death & Disease]
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