Researchers investigated the role of ALOX15+ M2 macrophages in the epithelial remodeling of eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP). Digital spatial transcriptome and single-cell sequencing analyses were used to characterize the epithelial remodeling and cellular infiltrate in eCRSwNP.
[Journal Of Allergy And Clinical Immunology]