NewslettersPancreatic Cell News Positive Feedback Regulation between Glycolysis and Histone Lactylation Drives Oncogenesis in Pancreatic Ductal Adenocarcinoma By Emily Salmini - May 7, 2024 0 The participation of histone lactylation in the growth and progression of PDAC was confirmed through inhibition of histone lactylation by glycolysis inhibitors or lactate dehydrogenase A knockdown both in vitro and in vivo. [Molecular Cancer] Full Article