Scientists investigated the mechanisms underlying the anti-inflammatory and anti-migratory functions of JQ1 and the genes targeted by JQ1 in lipopolysaccharide-activated human microglial clone 3 cells using RNA-sequencing.
[Scientific Reports]
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Baek, M., Yoo, E., Choi, H. I., An, G. Y., Chai, J. C., Lee, Y. S., Jung, K. H., & Chai, Y. G. (2021). The BET inhibitor attenuates the inflammatory response and cell migration in human microglial HMC3 cell line. Scientific Reports, 11(1), 8828. https://doi.org/10.1038/s41598-021-87828-1 Cite
