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H3K9ac of TGFβRI in Human Umbilical Cord: A Potential Biomarker for Evaluating Cartilage Differentiation and Susceptibility to Osteoarthritis via a Two-Step Strategy

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Two kinds of Wharton’s jelly-MSCs were applied to evaluate their chondrogenic potential in vitro through inducing chondrogenic differentiation as the first step of our strategy, one from newborns with intrauterine growth retardation (IUGR) and the other from normal newborns but treated with excessive cortisol during differentiation to simulate the excessive maternal glucocorticoid in the IUGR newborns.
[Stem Cell Research & Therapy]
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Qi, Y., Li, B., Wen, Y., Yang, X., Chen, B., He, Z., Zhao, Z., Magdalou, J., Wang, H., & Chen, L. (2021). H3K9ac of TGFβRI in human umbilical cord: a potential biomarker for evaluating cartilage differentiation and susceptibility to osteoarthritis via a two-step strategy. Stem Cell Research & Therapy, 12(1), 163. https://doi.org/10.1186/s13287-021-02234-8 Cite
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