In vitro studies showed that low-dose bisphenol A promoted the proliferation of human prostate fibroblasts and epithelial cells, and significantly upregulated the expression of cyclooxygenase-2 (COX-2) and L-PGDS in the cells.
[Scientific Reports]
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Wu, S., Huang, D., Su, X., Yan, H., Ma, A., Li, L., Wu, J., & Sun, Z. (2020). The prostaglandin synthases, COX-2 and L-PGDS, mediate prostate hyperplasia induced by low-dose bisphenol A. Scientific Reports, 10(1), 13108. https://doi.org/10.1038/s41598-020-69809-y Cite
