Home Newsletters Immune Regulation News Adaptive Immunity at the Crossroads of Autophagy and Metabolism

Adaptive Immunity at the Crossroads of Autophagy and Metabolism

0
The authors summarize and discuss the versatile roles of autophagy in regulating cellular metabolism and the implications of autophagy for immune cell function and fate, especially for T and B lymphocytes.
[Cellular & Molecular Immunology]
6445218 {6445218:BBNLXSRA} apa 50 1 160696 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3A%22zotpress-26031d90366cf51d5c3a6d0e155bb324%22%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22BBNLXSRA%22%2C%22library%22%3A%7B%22id%22%3A6445218%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Metur%20and%20Klionsky%22%2C%22parsedDate%22%3A%222021-03-30%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EMetur%2C%20S.%20P.%2C%20%26amp%3B%20Klionsky%2C%20D.%20J.%20%282021%29.%20Adaptive%20immunity%20at%20the%20crossroads%20of%20autophagy%20and%20metabolism.%20%3Ci%3ECellular%20%26amp%3B%20Molecular%20Immunology%3C%5C%2Fi%3E%2C%201%26%23x2013%3B10.%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41423-021-00662-3%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41423-021-00662-3%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.stemcellsciencenews.com%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D6445218%26amp%3Bitem_key%3DBBNLXSRA%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Adaptive%20immunity%20at%20the%20crossroads%20of%20autophagy%20and%20metabolism%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Shree%20Padma%22%2C%22lastName%22%3A%22Metur%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniel%20J.%22%2C%22lastName%22%3A%22Klionsky%22%7D%5D%2C%22abstractNote%22%3A%22The%20function%20of%20lymphocytes%20is%20dependent%20on%20their%20plasticity%2C%20particularly%20their%20adaptation%20to%20energy%20availability%20and%20environmental%20stress%2C%20and%20their%20protein%20synthesis%20machinery.%20Lymphocytes%20are%20constantly%20under%20metabolic%20stress%2C%20and%20macroautophagy%5C%2Fautophagy%20is%20the%20primary%20metabolic%20pathway%20that%20helps%20cells%20overcome%20stressors.%20The%20intrinsic%20role%20of%20autophagy%20in%20regulating%20the%20metabolism%20of%20adaptive%20immune%20cells%20has%20recently%20gained%20increasing%20attention.%20In%20this%20review%2C%20we%20summarize%20and%20discuss%20the%20versatile%20roles%20of%20autophagy%20in%20regulating%20cellular%20metabolism%20and%20the%20implications%20of%20autophagy%20for%20immune%20cell%20function%20and%20fate%2C%20especially%20for%20T%20and%20B%20lymphocytes.%22%2C%22date%22%3A%222021-03-30%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41423-021-00662-3%22%2C%22ISSN%22%3A%222042-0226%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41423-021-00662-3%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-03-31T06%3A13%3A49Z%22%7D%7D%5D%7D
Metur, S. P., & Klionsky, D. J. (2021). Adaptive immunity at the crossroads of autophagy and metabolism. Cellular & Molecular Immunology, 1–10. https://doi.org/10.1038/s41423-021-00662-3 Cite
Full Article
Exit mobile version