Researchers showed that extracellular vesicles isolated from mouse and human intestinal organoids modulated inflammatory responses of various immune cells including mouse bone-marrow derived-macrophages, dendritic cells, microglia cells, and human monocytes.
[Mucosal Immunology]
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Zhang, Y., Yan, Y., Meng, J., Girotra, M., Ramakrishnan, S., & Roy, S. (2021). Immune modulation mediated by extracellular vesicles of intestinal organoids is disrupted by opioids. Mucosal Immunology, 1–12. https://doi.org/10.1038/s41385-021-00392-9 Cite
