Scientists demonstrated that inhibition of protein synthesis during viral infection is sensed as a virulence strategy and initiates pyroptosis in human keratinocytes.
[Immunity]
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Orzalli, M. H., Prochera, A., Payne, L., Smith, A., Garlick, J. A., & Kagan, J. C. (2021). Virus-mediated inactivation of anti-apoptotic Bcl-2 family members promotes Gasdermin-E-dependent pyroptosis in barrier epithelial cells. Immunity, 0(0). https://doi.org/10.1016/j.immuni.2021.04.012 Cite
