Researchers also show that Aß plaque-associated NPA locally disassembles blood vessels, leaving behind vascular scars, and that microglial phagocytosis contributes to the local loss of endothelial cells.
[Nature Communications]
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Alvarez-Vergara, M. I., Rosales-Nieves, A. E., March-Diaz, R., Rodriguez-Perinan, G., Lara-Ureña, N., Ortega-de San Luis, C., Sanchez-Garcia, M. A., Martin-Bornez, M., Gómez-Gálvez, P., Vicente-Munuera, P., Fernandez-Gomez, B., Marchena, M. A., Bullones-Bolanos, A. S., Davila, J. C., Gonzalez-Martinez, R., Trillo-Contreras, J. L., Sanchez-Hidalgo, A. C., del Toro, R., Scholl, F. G., … Pascual, A. (2021). Non-productive angiogenesis disassembles Aß plaque-associated blood vessels. Nature Communications, 12(1), 3098. https://doi.org/10.1038/s41467-021-23337-z Cite
