The disease ranges in severity from asymptomatic through to severe acute respiratory distress requiring intensive care treatment and mechanical ventilation, which can lead to respiratory failure and death.
[Immunological Reviews]
7753456
{7753456:CT8QQWT2}
apa
50
1
162701
https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3A%22zotpress-03ab8f4f29693662e52c7d4c22a86e76%22%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22CT8QQWT2%22%2C%22library%22%3A%7B%22id%22%3A7753456%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22John%20et%20al.%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EJohn%2C%20A.%20E.%2C%20Joseph%2C%20C.%2C%20Jenkins%2C%20G.%2C%20%26amp%3B%20Tatler%2C%20A.%20L.%20%28n.d.%29.%20COVID-19%20and%20pulmonary%20fibrosis%3A%20A%20potential%20role%20for%20lung%20epithelial%20cells%20and%20fibroblasts.%20%3Ci%3EImmunological%20Reviews%3C%5C%2Fi%3E%2C%20%3Ci%3En%5C%2Fa%3C%5C%2Fi%3E%28n%5C%2Fa%29.%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2Fhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fimr.12977%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2Fhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fimr.12977%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.stemcellsciencenews.com%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D7753456%26amp%3Bitem_key%3DCT8QQWT2%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22COVID-19%20and%20pulmonary%20fibrosis%3A%20A%20potential%20role%20for%20lung%20epithelial%20cells%20and%20fibroblasts%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alison%20E.%22%2C%22lastName%22%3A%22John%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chitra%22%2C%22lastName%22%3A%22Joseph%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gisli%22%2C%22lastName%22%3A%22Jenkins%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Amanda%20L.%22%2C%22lastName%22%3A%22Tatler%22%7D%5D%2C%22abstractNote%22%3A%22The%20COVID-19%20pandemic%20rapidly%20spread%20around%20the%20world%20following%20the%20first%20reports%20in%20Wuhan%20City%2C%20China%20in%20late%202019.%20The%20disease%2C%20caused%20by%20the%20novel%20SARS-CoV-2%20virus%2C%20is%20primarily%20a%20respiratory%20condition%20that%20can%20affect%20numerous%20other%20bodily%20systems%20including%20the%20cardiovascular%20and%20gastrointestinal%20systems.%20The%20disease%20ranges%20in%20severity%20from%20asymptomatic%20through%20to%20severe%20acute%20respiratory%20distress%20requiring%20intensive%20care%20treatment%20and%20mechanical%20ventilation%2C%20which%20can%20lead%20to%20respiratory%20failure%20and%20death.%20It%20has%20rapidly%20become%20evident%20that%20COVID-19%20patients%20can%20develop%20features%20of%20interstitial%20pulmonary%20fibrosis%2C%20which%20in%20many%20cases%20persist%20for%20as%20long%20as%20we%20have%20thus%20far%20been%20able%20to%20follow%20the%20patients.%20Many%20questions%20remain%20about%20how%20such%20fibrotic%20changes%20occur%20within%20the%20lung%20of%20COVID-19%20patients%2C%20whether%20the%20changes%20will%20persist%20long%20term%20or%20are%20capable%20of%20resolving%2C%20and%20whether%20post-COVID-19%20pulmonary%20fibrosis%20has%20the%20potential%20to%20become%20progressive%2C%20as%20in%20other%20fibrotic%20lung%20diseases.%20This%20review%20brings%20together%20our%20existing%20knowledge%20on%20both%20COVID-19%20and%20pulmonary%20fibrosis%2C%20with%20a%20particular%20focus%20on%20lung%20epithelial%20cells%20and%20fibroblasts%2C%20in%20order%20to%20discuss%20common%20pathways%20and%20processes%20that%20may%20be%20implicated%20as%20we%20try%20to%20answer%20these%20important%20questions%20in%20the%20months%20and%20years%20to%20come.%22%2C%22date%22%3A%22%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fimr.12977%22%2C%22ISSN%22%3A%221600-065X%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1111%5C%2Fimr.12977%22%2C%22deleted%22%3A1%2C%22collections%22%3A%5B%2243ZBJFKZ%22%5D%2C%22dateModified%22%3A%222021-05-27T18%3A28%3A21Z%22%7D%7D%5D%7D
John, A. E., Joseph, C., Jenkins, G., & Tatler, A. L. (n.d.). COVID-19 and pulmonary fibrosis: A potential role for lung epithelial cells and fibroblasts. Immunological Reviews, n/a(n/a). https://doi.org/https://doi.org/10.1111/imr.12977 Cite
