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Role of Cytoplasmic Localization of Maspin in Promoting Cell Invasion in Breast Cancer with Aggressive Phenotype

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Scientists studied the biological function of cytoplasmic maspin in breast cancer cell lines. Subcellular localization of maspin in MDA-MB-231 breast cancer cells was mainly detected in the cytoplasm, whereas in MCF10A mammary epithelial cells, maspin was present in both cytoplasm and nucleus.
[Scientific Reports]

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