Scientists described common genetic and structural features of protective human antibodies from several individuals recognizing the trimer interface of the influenza A hemagglutinin head, a recently identified site of vulnerability.
[Journal of Clinical Investigation]
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Zost, S. J., Dong, J., Gilchuk, I. M., Gilchuk, P., Thornburg, N. J., Bangaru, S., Kose, N., Finn, J. A., Bombardi, R., Soto, C., Chen, E. C., Nargi, R. S., Sutton, R. E., Irving, R. P., Suryadevara, N., Westover, J. B., Carnahan, R. H., Turner, H. L., Li, S., … Jr, J. E. C. (2021). Canonical features of human antibodies recognizing the influenza hemagglutinin trimer interface. The Journal of Clinical Investigation. https://doi.org/10.1172/JCI146791 Cite
