Investigators showed that the nucleocapsid of SARS-CoV-2 inhibited host pyroptosis by blocking Gasdermin D cleavage. SARS-CoV-2-infected monocytes showed enhanced cellular interleukin 1b (IL-1b) expression, but reduced IL-1b secretion.
[EMBO Journal]
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SARS-CoV-2 nucleocapsid suppresses host pyroptosis by blocking Gasdermin D cleavage. (2021). The EMBO Journal, n/a(n/a), e108249. https://doi.org/10.15252/embj.2021108249 Cite
