Scientists reported SARS-CoV-2 specific T cell responses in infected adults and children and find that the acute and memory CD4+ T cell responses to structural SARS-CoV-2 proteins increase with age, whereas CD8+ T cell responses increase with time post-infection.
[Nature Communications]
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Cohen, C. A., Li, A. P. Y., Hachim, A., Hui, D. S. C., Kwan, M. Y. W., Tsang, O. T. Y., Chiu, S. S., Chan, W. H., Yau, Y. S., Kavian, N., Ma, F. N. L., Lau, E. H. Y., Cheng, S. M. S., Poon, L. L. M., Peiris, M., & Valkenburg, S. A. (2021). SARS-CoV-2 specific T cell responses are lower in children and increase with age and time after infection. Nature Communications, 12(1), 4678. https://doi.org/10.1038/s41467-021-24938-4 Cite
