Scientists showed a distinct mechanism by which SARS-CoV-2 N protein promoted NLRP3 inflammasome activation to induce hyperinflammation.
[Nature Communications]
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Pan, P., Shen, M., Yu, Z., Ge, W., Chen, K., Tian, M., Xiao, F., Wang, Z., Wang, J., Jia, Y., Wang, W., Wan, P., Zhang, J., Chen, W., Lei, Z., Chen, X., Luo, Z., Zhang, Q., Xu, M., … Wu, J. (2021). SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation. Nature Communications, 12(1), 4664. https://doi.org/10.1038/s41467-021-25015-6 Cite
