Home Newsletters Prostate Cell News The Role of Liquid Biopsies in Prostate Cancer Management

The Role of Liquid Biopsies in Prostate Cancer Management

0
Researchers describe recent advancements in isolation and detection technology and the strength and weaknesses of the three circulating biomarkers.
[Lab on a Chip]
6445218 {6445218:65FFZCFW} apa 50 1 165399 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3A%22zotpress-2423112a128be56e8aaf0cc6e99dd26b%22%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%2265FFZCFW%22%2C%22library%22%3A%7B%22id%22%3A6445218%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kim%20et%20al.%22%2C%22parsedDate%22%3A%222021-07-23%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKim%2C%20C.-J.%2C%20Dong%2C%20L.%2C%20Amend%2C%20S.%20R.%2C%20Cho%2C%20Y.-K.%2C%20%26amp%3B%20Pienta%2C%20K.%20J.%20%282021%29.%20The%20role%20of%20liquid%20biopsies%20in%20prostate%20cancer%20management.%20%3Ci%3ELab%20on%20a%20Chip%3C%5C%2Fi%3E.%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1039%5C%2FD1LC00485A%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1039%5C%2FD1LC00485A%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.stemcellsciencenews.com%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D6445218%26amp%3Bitem_key%3D65FFZCFW%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20role%20of%20liquid%20biopsies%20in%20prostate%20cancer%20management%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chi-Ju%22%2C%22lastName%22%3A%22Kim%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Liang%22%2C%22lastName%22%3A%22Dong%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sarah%20R.%22%2C%22lastName%22%3A%22Amend%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yoon-Kyoung%22%2C%22lastName%22%3A%22Cho%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kenneth%20J.%22%2C%22lastName%22%3A%22Pienta%22%7D%5D%2C%22abstractNote%22%3A%22Liquid%20biopsy%20has%20emerged%20as%20a%20complement%20to%20invasive%20tissue%20biopsy%20to%20guide%20cancer%20diagnosis%20and%20treatment.%20The%20common%20liquid%20biopsy%20biomarkers%20are%20circulating%20tumor%20cells%20%28CTCs%29%2C%20extracellular%20vesicles%20%28EVs%29%2C%20and%20circulating%20tumor%20DNA%20%28ctDNA%29.%20Each%20biomarker%20provides%20specific%20information%20based%20on%20its%20intrinsic%20characteristics.%20Prostate%20cancer%20is%20the%20second%20most%20common%20cancer%20in%20males%20worldwide.%20In%20men%20with%20low-grade%20localized%20prostate%20cancer%2C%20the%20disease%20can%20often%20be%20managed%20by%20active%20surveillance.%20For%20men%20who%20require%20treatment%2C%20the%205-year%20survival%20rate%20of%20localized%20prostate%20cancer%20is%20the%20highest%20among%20all%20cancer%20types%2C%20but%20the%20metastatic%20disease%20remains%20incurable.%20Metastatic%20prostate%20cancer%20invariably%20progresses%20to%20involve%20multiple%20bone%20sites%20and%20develops%20into%20a%20castration-resistant%20disease%20that%20leads%20to%20cancer%20death.%20The%20need%20to%20appropriately%20diagnose%20and%20guide%20the%20serial%20treatment%20of%20men%20with%20prostate%20cancer%20has%20led%20to%20the%20implementation%20of%20many%20studies%20to%20apply%20liquid%20biopsies%20to%20prostate%20cancer%20management.%20This%20review%20describes%20recent%20advancements%20in%20isolation%20and%20detection%20technology%20and%20the%20strength%20and%20weaknesses%20of%20the%20three%20circulating%20biomarkers.%20The%20clinical%20studies%20based%20on%20liquid%20biopsy%20results%20are%20summarized%20to%20depict%20the%20future%20perspective%20in%20the%20role%20of%20liquid%20biopsy%20on%20prostate%20cancer%20management.%22%2C%22date%22%3A%222021-07-23%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1039%5C%2FD1LC00485A%22%2C%22ISSN%22%3A%221473-0189%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fpubs.rsc.org%5C%2Fen%5C%2Fcontent%5C%2Farticlelanding%5C%2F2021%5C%2Flc%5C%2Fd1lc00485a%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-08-05T23%3A08%3A43Z%22%7D%7D%5D%7D
Kim, C.-J., Dong, L., Amend, S. R., Cho, Y.-K., & Pienta, K. J. (2021). The role of liquid biopsies in prostate cancer management. Lab on a Chip. https://doi.org/10.1039/D1LC00485A Cite
AbstractGraphical Abstract
Exit mobile version