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Chronological Genome and Single-Cell Transcriptome Integration Characterizes the Evolutionary Process of Adult T Cell Leukemia-Lymphoma

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Scientists developed and utilized a capture-based sequencing panel, which covered host hotspot genes and the full-length genome of human T-cell leukemia virus type-1, to investigate the clonal architecture of adult T-cell leukemia-lymphoma.
[Nature Communications]
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Yamagishi, M., Kubokawa, M., Kuze, Y., Suzuki, A., Yokomizo, A., Kobayashi, S., Nakashima, M., Makiyama, J., Iwanaga, M., Fukuda, T., Watanabe, T., Suzuki, Y., & Uchimaru, K. (2021). Chronological genome and single-cell transcriptome integration characterizes the evolutionary process of adult T cell leukemia-lymphoma. Nature Communications, 12(1), 4821. https://doi.org/10.1038/s41467-021-25101-9 Cite
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