The authors demonstrate that TGFβ signaling was required to maintain naïve human PSCs (hPSCs). The downstream effector proteins – SMAD2/3 – bound common sites in naïve and primed hPSCs, including shared pluripotency genes.
[eLife]
7992332
{7992332:2GHZHJZN}
apa
50
1
166345
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