Differential Virus-Specific IFN-Gamma Producing T Cell Responses to Marek’s Disease Virus in Chickens with B19 and B21 MHC Haplotypes

The frequencies of IFN-gamma producing pp38 and MEQ-specific T cell responses were determined in line N and line P2a chickens after infection with vaccine and/or virulent strains of Marek’s disease virus using both standard ex vivo and cultured chIFN-gamma ELISPOT assays.