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SARS-CoV-2 Antigen Exposure History Shapes Phenotypes and Specificity of Memory CD8+ T Cells

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The authors utilize major histocompatibility complex multimers with single-cell RNA sequencing to profile SARS-CoV-2-responsive T cells ex vivo from humans with one, two or three antigen exposures, including vaccination, primary infection and breakthrough infection.
[Nature Immunology]

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