SARS-CoV-2 BA.1 Variant Is Neutralized by Vaccine Booster-Elicited Serum, but Evades Most Convalescent Serum and Therapeutic Antibodies

Researchers measured neutralization of the Omicron BA.1 variant pseudovirus by post-vaccination serum samples after two and three immunizations with the Pfizer/BioNTech162b2 SARS-CoV-2 mRNA vaccine, convalescent serum samples from unvaccinated individuals infected by different variants, and clinical-stage therapeutic antibodies.