NewslettersHematopoiesis News Regulation of Erythropoiesis by the Hypoxia-Inducible Factor Pathway: Effects of Genetic and Pharmacological Perturbations By lbeveridge - July 5, 2022 0 Mutations in the genes encoding erythropoietin (EPO), EPO receptor, HIF-2α, prolyl hydroxylase domain protein 2, or von Hippel–Lindau protein caused familial erythrocytosis. [Annual Review of Medicine] Abstract