Hemostasis Without Clot Formation – How Platelets Guard the Vasculature in Inflammation, Infection, and Malignancy

The authors summarize previously recognized and more recent studies that have elucidated how anucleate, small platelets manage to maintain vascular integrity when faced with challenges of infection, sterile inflammation and even malignancy. They dissect how platelets are recruited to the vascular wall, how they identify sites of injury, and how they prevent hemorrhage as single cells.