Not Just for Lymphoid Cells: The Role of the Noncanonical NF-κB Signaling Pathway in Early and Late Myelopoiesis with a Focus on Hypereosinophilic Disorders

The authors discuss the molecular machinery within the noncanonical NF-κB pathway, crosstalk with the canonical NF-κB pathway, murine models of noncanonical signaling, as well as how aberrations in this pathway manifest in leukemic or hyperinflammatory disease with a focus on Hypereosinophilic syndrome.