NewslettersImmune Regulation News Ad-SGE-DKK3 Gene Therapy Overcomes Resistance to Immune Checkpoint Blockade in Pleural Mesothelioma By Jamie Kang - April 15, 2025 0 30 Researchers performed preclinical studies to elucidate Dickkopf WNT Signaling Pathway Inhibitor 3 (DKK3)’s role in immune checkpoint inhibitors-resistant mouse mesothelioma. [Clinical Cancer Research] Abstract