Scientists elucidated the molecular mechanisms underlying perillaldehyde-mediated endothelial protection through the establishment of endothelium-specific TRPM2 transgenic and knockout murine models.
[International Immunopharmacology]
Competitive Inhibition of Ephrin-A1 and EphA2 Binding by Perillaldehyde Leads to Decreased TRPM2 Expression and Reduced Mitochondrial Damage in Vascular Endothelial Cells
