Investigators describe in detail the damage-associated molecular patterns that induce or aggravate neuroinflammation in neurodegenerative diseases including mtDNA, mitochondrial unfolded protein response, mitochondrial reactive oxygen species, adenosine triphosphate, transcription factor A mitochondria, cardiolipin, cytochrome c, mitochondrial Ca2+ and iron.
[Acta Pharmacologica Sinica]
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