| Vol. 7.21 – 20 June, 2022 |
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| The authors identified the monocyte- and macrophage-derived cytokine meteorin-like as a driver of postinfarction angiogenesis and high-affinity ligand for the stem cell factor receptor KIT receptor tyrosine kinase. [Science] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists presented a functional characterization of Schizophrenia-derived brain microvascular endothelial-like cells, the counterpart of the neurovascular crosstalk, revealing an intrinsically defective blood–brain barrier phenotype. [Molecular Psychiatry] |
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| Proteomic analysis showed a higher abundance of the extracellular matrix small leucine-rich proteoglycan Fibromodulin in the conditioned medium of differentiated glioma cells, the equivalent of glioma non-cancer stem cells, compared to that of glioma stem-like cells. [eLife] |
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| Researchers identified ECFAK as a regulator of retinal vascular patterning by controlling ERG protein degradation via TRIM25/USP9x. [Development] |
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| Tube formation and migration of primary human retinal microvascular endothelial cells and tube-like structure formation, migration, invasion of uveal melanoma cells were evaluated after CD146 inhibition. [Cellular Oncology] |
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| Investigators examined whether CD4+ memory T cells could drive endothelial cell inflammatory responses. [Frontiers in Immunology] |
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| The authors reported that expression of active and wild‐type RhoA but not dominant‐negative RhoA significantly inhibited endothelial cell proliferation, migration, tube formation, and angiogenic sprouting in vitro. [Journal of the American Heart Association] |
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| Researchers highlighted the significant crosstalk between tumor cells and the endothelium including increased von Willebrand Factor secretion which may have contributed to tumor metastasis. [Journal of Thrombosis and Haemostasis] |
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| To explore the expression of NEAT1 and miR-125b-5p and the proliferation activity, migration ability, and angiogenesis ability of human retinal microvascular endothelial cells, RT-qPCR, CCK-8, Transwell, and tube formation assays were performed. [Experimental Eye Research] |
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| Recent technical advances, such as precise cell fate mapping, time-lapse imaging, genome editing, and single-cell RNA sequencing, have shed new light on the role of venous endothelial cells in angiogenesis under both normal and pathological conditions. [Experimental & Molecular Medicine] |
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| Inozyme Pharma, Inc. announced a partnership with Rady Children’s Institute for Genomic Medicine to advance and evaluate a novel newborn screening technology to facilitate the diagnosis of genetic diseases. [Inozyme Pharma, Inc.] |
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| SoniVie announced that the US FDA granted Investigational Device Exemption (IDE) approval for its “REDUCED1” Pilot study to treat resistant hypertension patients with renal artery denervation using TIVUS™, its innovative ultra-sound ablation system. [SoniVie (Cision US, Inc.)] |
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| September 19 – 20, 2022 Vejle, Denmark |
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| Aarhus University – Aarhus, Denmark |
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| L’institut du Thorax Research Unit – Nantes, France |
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| University of California, San Diego – La Jolla, California, United States |
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| Huntington Medical Research Institutes – Pasadena, California, United States |
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| University of Pittsburgh School of Medicine – Pittsburgh, Pennsylvania, United States |
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