Prostate Cell News

Prostate Cell News is an online resource summarizing the latest prostate cell research.

Integrative Surface Antigen Profiling of KLK2 and STEAP1 in Advanced Prostate Cancer

May 29, 2026

[Molecular Cancer Research] Scientists characterized the expression landscape of KLK2 and STEAP1 in metastatic CRPC and defined associated transcriptomic, genomic, and epigenomic features.

PU.1 Is a Mediator of the Reactive Stromal Response Associated with Castration-Resistant Prostate Cancer

May 29, 2026

[Communications Biology] Researchers characterized the molecular composition of the tumor microenvironment of androgen-sensitive and CRPC by utilizing patient-derived xenograft models.

Ferroptosis Vulnerability of Enzalutamide Resistant Prostate Cancer Conferred by ACSL4 Overexpression and GPX4 Antagonism

May 29, 2026

[Cell Death & Disease] Scientists utilized their established enzalutamide-resistant prostate cancer cell lines to reveal a vulnerability of these cancer cells to GPX4-targeted ferroptosis.

Interplay of the 3D Genome and Epigenome in Androgen-Driven Prostate Cancer

May 29, 2026

[Epigenomics] Scientists presented a perspective on how the spatial architecture of the epigenome, including 3D chromatin structure and dynamics, orchestrates dysregulation of transcription factor networks that help to drive disease progression in androgen-driven prostate cancer.

Integrative Advances in Biomarker-Driven Prostate Cancer Management from Genomic Discovery to Precision Oncology

May 29, 2026

[Discover Oncology] The authors review recent advances in prostate cancer biomarkers, encompassing genetic, proteomic, liquid biopsy, and imaging-based approaches. Genetic mutations inform disease prognosis and therapy selection, while proteomic biomarkers elucidate molecular mechanisms and therapeutic targets.

Gasdermin D Antagonizes Immunosuppression in Prostate Cancer by Inducing LAMC2 Degradation to Block M2 Macrophage Polarization

May 28, 2026

[Journal for Immunotherapy of Cancer] Researchers investigated the potential non-pyroptotic mechanism of action of gasdermin D (GSDMD) in preventing prostate cancer (PCa) immune evasion. They revealed a novel non-pyroptotic pathway through which GSDMD inhibits PCa immune evasion by targeting laminin subunit gamma-2 (LAMC2) for degradation.

Single-Cell and Spatial RNA Sequencing in Prostate Cancer

May 28, 2026

[Nature Reviews Urology] Spatial transcriptomics enables the characterization of tumor architecture using spatial resolution at the single-cell or multi-cell level. These approaches also permit bioinformatic inference of large-scale copy number variants, enabling integrated genomic–transcriptomic analysis of clonal evolution and therapy resistance.

2026 Publishing Award Recipient Advances Clarity in Prostate Cancer Screening

May 28, 2026

[AAPA] Dr. Michael Gerlach has built his career at the intersection of clinical care, leadership, and evidence‑based medicine, guided by a longstanding commitment to improving outcomes for patients navigating difficult health decisions. He is the recipient of the 2026 AAPA Publishing Award.

Bobba Receives Young Investigator Award for Prostate Cancer Research

May 28, 2026

[University of Tennessee] Dr. Kondapa Naidu Bobba has been selected to receive the 2026 Young Investigator Award, which is jointly supported by the Prostate Cancer Foundation and Society of Nuclear Medicine and Molecular Imaging to advance important prostate cancer research among early-career physicians and scientists.

FARP1 Mediates cMET-Driven Motility in Androgen-Independent Prostate Cancer Cells

May 28, 2026

[Endocrinology] Scientists shed light on the distinctive contribution of Rac guanine nucleotide exchange factors to prostate cancer cell motility via receptor tyrosine kinases and identifed FARP1 as a crucial cMET-invasive effector.

VprBP Drives Prostate Tumorigenesis by Its Kinase Activity Targeting Histone H2A

May 28, 2026

[Cell Communication and Signaling] Researchers reported that VprBP is highly expressed in prostate cancer cells and inactivates a group of genes encoding critical regulators of cell growth and proliferation in a manner dependent on its kinase activity toward H2AT120.

A Forward Genetic Screen Identifies Sirtuin1 As a Driver of Neuroendocrine Prostate Cancer

May 28, 2026

[Journal of Experimental Medicine] Gain- and loss-of-function studies in human prostate cancer cells and mouse neuroendocrine prostate cancer (NEPC) organoids confirmed that sirtuin 1 promotes NEPC, while pharmacological inhibition suppresses it.

Published since 2010, Prostate Cell News compiles top scientific journal articles covering the characterization, behavior, and culturing of prostate cells. Additionally, our editorial team curates the latest press releases, technical advances, jobs, and events relevant to the prostate cell research community. Prostate Cell News saves scientists valuable time while keeping them informed in their field, facilitating the rapid exchange of cutting edge research updates and science news.