Downregulation of Large-Conductance Ca2+-Activated K+ Channels in Human Umbilical Arterial Smooth Muscle Cells in Gestational Diabetes Mellitus

Scientists investigated the changes in large-conductance Ca2+-activated K+ channels from human umbilical arterial smooth muscle cells experiencing gestational diabetes mellitus.
[Life Sciences]
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Prenatal Exposure to Poly-/Per-Fluoroalkyl Substances Is Associated with Alteration of Lipid Profiles in Cord-Blood

Researchers combined determination of bile acids and molecular lipids by liquid chromatography with ultra-high-resolution mass spectrometry, and separately quantified cord blood concentrations of sixteen poly-/per-fluoroalkyl substances in a cohort of Chinese infants in a cross-sectional study.
[Metabolomics]
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Comparing Cord Blood Transplantation and Matched Related Donor Transplantation in Non-Remission Acute Myeloid Leukemia

Scientists investigated the impact of cord blood transplantation, compared to human leukocyte antigen-matched related donor transplantation.
[Leukemia]
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Impact of Donor Types on Reduced-Intensity Conditioning Allogeneic Stem Cell Transplant for Mature Lymphoid Malignancies

Scientists retrospectively compared the outcomes of reduced-intensity conditioning transplantation from matched related donors matched unrelated donors, and umbilical cord blood for mature lymphoid malignancies.
[Bone Marrow Transplantation]
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Comparing Cord Blood Transplantation and Matched Related Donor Transplantation in Non-remission Acute Myeloid Leukemia

Researchers investigated the impact of cord blood transplantation, compared to human leukocyte antigen-matched related donor transplantation.
[Leukemia]
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Affimed Announces 100% Objective Response Rate at Highest Dose in Phase I-II Study of Cord Blood-Derived Natural Killer Cells Pre-complexed with Innate Cell Engager AFM13 for CD30-Positive Lymphomas

Affimed N.V. announced interim clinical results from the investigator-initiated phase I-II study at The University of Texas MD Anderson Cancer Center, evaluating cbNK cells pre-complexed with Affimed’s innate cell engager AFM13.
[Affimed N.V.]
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LncRNA MEG3 Alleviates PFOS Induced Placental Cell Growth Inhibition through Its Derived miR-770 Targeting PTX3

Scientists investigated the function of long non-coding RNA MEG3 and its derived miR-770 in PFOS-induced placental toxicity.
[Environmental Pollution]
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Prenatal Metal Exposure, Cord Blood DNA Methylation and Persistence in Childhood: An Epigenome-Wide Association Study of 12 Metals

Researchers analyzed the extent to which metals measured in maternal erythrocytes were associated with differentially methylated positions and regions in cord blood and tested if associations persisted in blood collected in mid-childhood.
[Clinical Epigenetics]
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Prospective Associations of Early Pregnancy Metal Mixtures with Mitochondria DNA Copy Number and Telomere Length in Maternal and Cord Blood

Researchers evaluated individual and joint associations of prenatal metals with mitochondrial DNA copy number and telomere length in maternal and cord blood as biomarkers of inflammation and oxidative stress.
[Environmental Health Perspectives]
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The Coevolution of Placentation and Cancer

The authors conclude that many similarities between trophoblast and cancer cells are shared with other, phylogenetically older processes than placentation.
[Annual Review of Animal Biosciences]
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MiR-455-5p Upregulation in Umbilical Cord Mesenchymal Stem Cells Attenuates Endometrial Injury and Promotes Repair of Damaged Endometrium via Janus Kinase/Signal Transducer and Activator of Transcription 3 Signaling

Scientists investigated the specific impacts of umbilical cord mesenchymal stem cells overexpressing miR-455-5p in intrauterine adhesions.
[Bioengineered]
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