Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
Endothelial Cell News
Endothelial Cell News is an online resource dedicated to the latest research studying the endothelium, blood vessels, and angiogenesis.
Subscribe|Follow Us On
SULF1’s Role in Endothelial Senescence and Atherosclerosis: Insights from Single-Cell and Bulk Transcriptomics
[Journal of Inflammation Research] Investigators highlight the critical role of endothelial senescence in atherosclerosis and identify SULF1 as a key contributor to endothelial senescence and atherogenesis.
Multidimensional Dynamic Optical Imaging Unveils Anesthetic-Driven Hemispheric Lateralization in Blood-Brain Barrier Homeostasis
[Science Advances] Scientists found that isoflurane facilitates hemispheric lateralization in blood-brain barrier permeability, leading to different responses between the left and right hemispheres.
Distinguishing Subtypes of Endothelial Cells in the Mouse Aorta
[Proceedings of The National Academy of Sciences of The United States of America] Contrary to the assumption that all endothelial cells originated from the luminal surface, investigators identified two distinct sites of origin: aortic lumen and peri-aortic microvascular.
Endothelial Cells Sialylate IgG within the FcRn-Mediated Recycling Pathway
[Proceedings of The National Academy of Sciences of The United States of America] The authors found that IgG sialylation occurs in the subcellular compartments of the FcRn-mediated IgG recycling pathway of endothelial cells.
Pharmacological Activation of p53 Induces Dose-Dependent Changes in Endothelial Cell Fate during Angiogenic Sprouting
[Cell Death & Disease] Using non-genotoxic small molecule and stapled peptide compounds to pharmacologically activate p53 via MDM2 inhibition, scientists demonstrated that graded levels of p53 induce distinct cellular fates in normal endothelial cells.
Blockade of Mitochondrial Components Release by Exosome Pathway Promotes the Pathogenesis of Fuchs Endothelial Corneal Dystrophy
[Cell Death Discovery] Researchers identified the protein changes of aqueous humor (AH) in patients with Fuchs endothelial corneal dystrophy and investigated in more detail the relationship between AH and corneal endothelium.
ARHGEF15 Promotes Endothelial Cell Migration through the Regulation of STAT3 Signaling
[Current Medical Science] The Rho guanine nucleotide exchange factor 15 (ARHGEF15) gene was overexpressed or knocked down in HUVECs, and the results were validated via qRT-PCR and Western blotting.
Cardiac Lymphatic System and Coronary Heart Disease: Associations, Mechanisms, and Therapeutic Strategies
[European Journal of Pharmacology] Investigators summarize the roles of lipid metabolism, immune cells, and inflammatory responses in the onset and progression of coronary heart disease and systematically review the structure, function, detection methods, and regulatory mechanisms of lymphatic vessels.
EyeYon Medical Ltd. Receives FDA IDE Approval to Initiate US Clinical Study of EndoArt®, the First Artificial Endothelial Layer for Corneal Edema
[EyeYon Medical (PR Newswire)] EyeYon Medical Ltd. announced that the US FDA has granted Investigational Device Exemption (IDE) approval to initiate a US clinical study of EndoArt®, the world's first synthetic endothelial layer for the treatment of chronic corneal edema.
Lipid Nanoparticle Library Screen Reveals Lymphatic Endothelial Cell-Targeting Lipid Nanoparticle for Delivering Vascular Endothelial Growth Factor C mRNA after Lymphatic Injury
[ACS Nano] Researchers identified and validated several lipid nanoparticles (LNP) formulations optimized for high lymphatic endothelial cells uptake when administered Iintradermal and compared their efficacy for delivery of functional mRNA with that of free mRNA and mRNA delivered with a commercially available MC3-based LNP.
Reconstruction of the Lymphatic System by Transplantation of a Centrifuge-Based Bioengineered Lymphatic Tissue
[Nature Communications] Scientists demonstrated that bioengineered tissues with a lymphatic network containing lymphatic endothelial cells and mesenchymal stem/stromal cells fabricated by a centrifugal cell stacking technique effectively treat secondary lymphedema.
MAPK Signaling and Angiopoietin-2 Contribute to Endothelial Permeability in Capillary Malformations
[Proceedings of The National Academy of Sciences of The United States of America] Investigators have shown the involvement of the MAPK pathway and the pro-angiogenic molecule ANGPT2 in endothelial permeability, suggesting a potential target in GNAQ p.R183Q-driven capillary malformations.
Specific research topics covered in Endothelial Cell News include the roles of endothelial cells in the regulation of physiological processes, as well as their implications in tumor progression, cardiovascular disease, endometriosis, wound healing, tissue regeneration and other diseases and disorders. We also provide updates on the latest job postings and upcoming events, helping connect everyone within the endothelial cell research field.
