1-Pyrroline-5-Carboxylate Inhibits T Cell Glycolysis in Prostate Cancer Microenvironment by SHP1/PKM2/LDHB Axis

Investigators produced an antibody for targeting 1-Pyrroline-5-Carboxylate (P5C) by monoclonal technique and verified that the antibody could oppose the influence of P5C The antibody also inhibited the growth of prostate tumors in an animal model.