Pancreatic Cell News is an online publication and email newsletter providing updates on the latest pancreatitis, diabetes, and pancreatic cancer research.
Pancreatic Cell News is a weekly newsletter that highlights recent top articles in the field of pancreatic cell research. These articles have been carefully selected from high-impact, peer-reviewed academic journals by our experienced editorial team. We cover topics including pancreatic cell culture, pancreatitis, diabetes, and pancreatic cancer. We also feature the latest industry and policy news alongside job postings and upcoming events to keep scientists current while saving them valuable time.
Pancreatic carcinoma (PC) is a severe disease associated with high mortality. To identify biomarkers for early diagnosis and therapy, three mRNA microarray datasets and two miRNA datasets were selected, and combinative analysis was performed by GEO2R.
The mechanisms of obesity and diabetes and the crosstalk between these diseases are still ambiguous. The authors clarified and explained the role of VGF peptides in the brain, pancreas, and adipose tissue in the development of obesity.
Researchers presented ultrasound imaging of nanodroplet (ND) contrast-agent accumulation within the islet. ND accumulation is dependent on immune infiltration; therefore, it tracked presymptomatic type I diabetes development and progression to diabetes
[Proceedings of the National Academy of Sciences of the United States of America]
Researchers investigated the short-term effect of 1α,25(OH)2 vitamin D3 and cholecalciferol on the glycemia and insulin sensitivity of control and dexamethasone-induced insulin-resistance in rats.
Precigen ActoBio, announced additional positive interim data from the ongoing Phase 1b/2a clinical study investigating AG019 ActoBioticsâ„¢ for the treatment of recent-onset type 1 diabetes.
ATP synthase inhibitory factor subunit 1 (IF1) is a mitochondrial protein interacting with ATP synthase to inhibit its enzyme activity. Scientists investigated islets freshly isolated from mouse lines with global inhibitory factor subunit 1 knockout (IF1−/−) and overexpression.
Scientists proposed that intracellular accumulation of a nonfunctional chymotrypsinogen B2 protein led to endoplasmic reticulum stress and pancreatic inflammation, which might explain the increased pancreatic cancer risk in carriers of CTRB2 exon 6 deletion alleles.
T.H.A.C SA, a biopharmaceutical Company which develops a new class of drugs for the early treatment of type 2 diabetes mellitus (T2DM), announces the acquisition of an international patent submitted by INSERM, Hospitals of Paris, INRA and University of Paris. This patent protects the drug candidate of THAC and its use for the protection of oxygen sensitive bacteria, for example in the gut microbiota. The Company reserves the right to submit a divisionary application in the coming months.
Researchers developed a comprehensive and highly tuneable ex vivo model of pancreatic ductal adenocarcinoma based on the 3D co-assembly of peptide amphiphiles with custom ECM components.
Scientists performed RNA pull-down, cycloheximide-chase, and ubiquitination assays to determine the effect of SOX2OT on FUS ubiquitination, and explored the specific regulatory mechanism of SOX2OT–FUS axis in pancreatic cancer cell migration, invasion, in vivo tumor growth, and metastasis through RNA sequencing.
Scientists identified the role and molecular mechanisms of ZFAS1 in pancreatic cancer. The expression of ZFAS1, miR-497-5p and HMGA2 in pancreatic cancer tissues was detected by qRT-PCR.
