Prostate Cell News

Prostate Cell News is an online resource summarizing the latest prostate cell research.

Targeting Secreted PLA Interactions with EGFR and Vimentin to Arrest Prostate Tumor Growth

December 22, 2025

[Cell Death & Disease] Scientists highlighted that the secreted phospholipase A2 human group IIA (contributes to prostaste cancer pathology primarily through specific protein-protein interactions.

73 Million SEK from the Swedish Cancer Society to MEB Researchers

December 19, 2025

[Karolinska Institute] The Swedish Cancer Society has announced its research grants for 2025. Around 73 million has been awarded to researchers at the Department of Medical Epidemiology and Biostatistics at Karolinska Institute.

Research to Catch Prostate Cancer Earlier Gets Grant

December 19, 2025

[Otago Daily Times] University of Otago pathology and molecular medicine researcher Dr. Jim Smith has received a Health Research Council grant to create a targeted DNA methylation-based blood test to detect prostate cancer earlier.

CDC7 Is a Targetable Regulator of Advanced Prostate Cancer

December 19, 2025

[Scientific Reports] Scientists demonstrated that CDC7 is highly expressed in treatment-resistant prostate cancer, with even higher levels observed in treatment-resistant prostate cancer with neuroendocrine phenotype.

Docetaxel Induced Activation of GSDME Pathway and Pyroptosis Enhance Immune Lethality in Prostate Cancer Cells

December 19, 2025

[Journal of Experimental & Clinical Cancer Research] The authors explored the specific molecular mechanism by which docetaxel enhances immunotherapy, with the aim of providing new insights for the immunotherapy of prostate cancer patients.

Menin-Driven mTOR Signaling Sustains Taxane Resistance in CRPC and Reveals a Targetable Vulnerability for Combination Therapy

December 19, 2025

[Cell Communication and Signaling] Researchers established docetaxel-resistant CRPC models and performed an epigenetic drug screen, identifying MLL-Menin and MLL-WDR5 inhibitors as potent agents capable of restoring taxane sensitivity through G2/M arrest and apoptosis induction.

PROCA11 Early Activation Fuels Prostate Cancer Neuroendocrine Traits by Regulating Cell Survival and Migration

December 19, 2025

[Iscience] Using a prostate cancer model mimicking the onset of castration-resistant and neuroendocrine phenotypes, researchers uncovered rapid lncRNA changes, with PROCA11 emerging as the most prominent.

CDC7 Is a Targetable Regulator of Advanced Prostate Cancer

December 18, 2025

[Scientific Reports] The authors demonstrated that CDC7 is highly expressed in treatment-resistant prostate cancer, with even higher levels observed in treatment-resistant prostate cancer with neuroendocrine phenotype.

The Multifaceted Role of Androgen Receptor Signaling in Immunity: Implications for Oncology

December 17, 2025

[Molecular Cancer Research] Scientists discuss the current evidence for the functional effects of androgen receptor signaling within the major immune cell compartments of the innate and adaptive immune systems.

Stromal-Derived High-Molecular-Weight Hyaluronan Mediates Radioresistance in the Prostate Cancer Microenvironment

December 17, 2025

[International Journal of Radiation Biology] Researchers suggest that stromal cells may contribute to the radioresistant tumor microenvironment in prostate cancer partly through alterations in high-molecular-weight hyaluronan.

SLC45A2 Drives Prostate Cancer Progression through Tumor Promotion and Immune Suppression

December 15, 2025

[Scientific Reports] Functional experiments showed that SLC45A2 knockdown inhibited the proliferation and migration of LNCaP and DU145 cells, while SLC45A2 overexpression reversed these effects.

Reprogramming the GRHL2−CDK19 Axis by Gene Therapy Alleviates Prostate Aging

December 5, 2025

[Nature Aging] Scientists integrated single-nucleus transcriptomics and histological analyses to elucidate the aging mechanisms of the primate prostate.

Published since 2010, Prostate Cell News compiles top scientific journal articles covering the characterization, behavior, and culturing of prostate cells. Additionally, our editorial team curates the latest press releases, technical advances, jobs, and events relevant to the prostate cell research community. Prostate Cell News saves scientists valuable time while keeping them informed in their field, facilitating the rapid exchange of cutting edge research updates and science news.