Prostate Cell News

Prostate Cell News is an online resource summarizing the latest prostate cell research.

Spatial Multi-Omics Identifies Aggressive Prostate Cancer Signatures Highlighting Pro-Inflammatory Chemokine Activity in the Tumor Microenvironment

November 20, 2025

[Nature Communications] Investigators interrogated spatially resolved multi-omics data to find molecular stratifiers of aggressive prostate cancer.

EZH2 Suppression Diversifies Prostate Cancer Lineage Variant Evolution and Lacks Efficacy in Inhibiting Disease Progression

November 20, 2025

[Cancer Research] As inhibitors of the histone methyltransferase EZH2 are being evaluated clinically for the treatment of advanced prostate cancer (PrCa), researchers investigated here how EZH2 affects PrCa lineage plasticity.

MYC and P53 Alterations Cooperate through VEGF Signaling to Repress Cytotoxic T-Cell and Immunotherapy Responses in Prostate Cancer

November 20, 2025

[Cancer Research] Using innovative electroporation-based mouse models, scientists generated distinct genetic subtypes of CRPC found in patients and uncovered unique immune microenvironments.

KDM3B Regulates Postradiation Fibrotic Responses in Prostate Stroma via N6-Methyladenosine Modification of LOX

November 20, 2025

[International Journal of Radiation Oncology Biology Physics] Dietary α-ketoglutarate supplementation may serve as a mechanism-based strategy to alleviate radiation toxicity in patients with prostate cancer, offering a potential therapeutic pathway to improve treatment outcomes.

GLP1 Receptor Agonism Alters Growth and Therapeutic Response in Prostate Cancer

November 20, 2025

[Endocrine-Related Cancer] In prostate cancer models, semaglutide decreased cell proliferation, glycolytic function, and phospho-kinase-mediated signaling.

Osteocytes Under Mechanical Loading Regulate PC-3 Cancer Cell-Mineral Interactions during Early-Stage Metastasis to Bone

November 20, 2025

[Advanced Biology] The inhibitory role of mechanical loading of osteocytes on the early-stage metastasis of the endosteal surface during prostate cancer bone metastasis was demonstrated.

Therapy-Induced Senescence in Prostate Cancer: Mechanisms, Therapeutic Strategies, and Clinical Implications

November 20, 2025

[Gene] The authors explore the molecular mechanisms of senescence, the diverse therapeutic strategies that induce it, and the dual roles it plays in prostate cancer progression and treatment resistance.

Curium Announces First Commercial Doses of Diagnostic Radiopharmaceutical in Czech Republic and Slovakia for Patients with Prostate Cancer

November 20, 2025

[Curium] Curium announced that patients in the Czech Republic and Slovakia received the first doses of diagnostic radiopharmaceuticals used to indicate the detection of prostate-specific membrane antigen-positive lesions with positron emission tomography in patients with prostate cancer.

Inhibition of Nuclear ROCK2 by a Novel Thiourea Derivative Induces Potent Antitumor Effects through PTEN/FOXO1 Pathway Restoration in Prostate Cancer

November 14, 2025

[Bioorganic Chemistry] The authors identified compound 25, a novel thiourea derivative, as a potent and selective anticancer agent. Among structurally related analogs, 25 exhibited the strongest antiproliferative activity in prostate cancer cells.

PhD Candidate Katherine Murphy Receives NIH Grant for Innovative Prostate Cancer Research

November 7, 2025

[UMass Chan Medical School] UMass Chan Medical School PhD candidate Katherine Murphy has received a Ruth L. Kirschstein National Research Service Award Individual Predoctoral Fellowship for her prostate cancer research in the lab of Marcus Ruscetti, PhD, assistant professor of molecular, cell & cancer biology.

Tackling Treatment-Resistant Prostate Cancer

November 7, 2025

[University of Wisconsin–Madison] A five-year, $12.5 million grant has been awarded to researchers at University of Wisconsin–Madison to investigate metastatic, or advanced stage, prostate cancer, the second most common cause of cancer death in men.

Chimeric Antigen Receptor-Based Cell Therapy for Treating Urological Tumors

November 7, 2025

[Current Urology Reports] The authors summarize the applications of CAR cell therapy in the following 3 major urological tumors: renal cell carcinoma, bladder cancer, and prostate cancer.

Published since 2010, Prostate Cell News compiles top scientific journal articles covering the characterization, behavior, and culturing of prostate cells. Additionally, our editorial team curates the latest press releases, technical advances, jobs, and events relevant to the prostate cell research community. Prostate Cell News saves scientists valuable time while keeping them informed in their field, facilitating the rapid exchange of cutting edge research updates and science news.