Prostate Cell News

Prostate Cell News is an online resource summarizing the latest prostate cell research.

NSD2 Targeting Reverses Plasticity and Drug Resistance in Prostate Cancer

November 26, 2025

[Nature] The authors showed that plasticity-associated treatment resistance in CRPC can be reversed through the inhibition of NSD2, a histone methyltransferase.

ACTC1 Promotes Tumor Progression by Upregulating BMP4 Expression in Prostate Cancer

November 25, 2025

[BMC Cancer] Integrative analysis of public datasets and immunohistochemistry revealed that ACTC1 is upregulated in prostate cancer.

Targeting FZD6 Creates Therapeutically Actionable Vulnerabilities for Advanced Prostate Cancer

November 25, 2025

[Oncogene] Scientists showed that frizzled (FZD) 6 is the most highly expressed and frequently amplified Wnt receptor in advanced human prostate cancers.

Effect of TGF-β Mediated Phenotypic Changes on Prostate Cancer Cell Anoikis Response

November 24, 2025

[Oncogene] Scientists investigated how TGF-β regulated mesenchymal epithelial transition phenotypic interconversions to enhance anoikis response in pre-clinical models of prostate cancer.

Spatial Multi-Omics Identifies Aggressive Prostate Cancer Signatures Highlighting Pro-Inflammatory Chemokine Activity in the Tumor Microenvironment

November 20, 2025

[Nature Communications] Investigators interrogated spatially resolved multi-omics data to find molecular stratifiers of aggressive prostate cancer.

EZH2 Suppression Diversifies Prostate Cancer Lineage Variant Evolution and Lacks Efficacy in Inhibiting Disease Progression

November 20, 2025

[Cancer Research] As inhibitors of the histone methyltransferase EZH2 are being evaluated clinically for the treatment of advanced prostate cancer (PrCa), researchers investigated here how EZH2 affects PrCa lineage plasticity.

MYC and P53 Alterations Cooperate through VEGF Signaling to Repress Cytotoxic T-Cell and Immunotherapy Responses in Prostate Cancer

November 20, 2025

[Cancer Research] Using innovative electroporation-based mouse models, scientists generated distinct genetic subtypes of CRPC found in patients and uncovered unique immune microenvironments.

KDM3B Regulates Postradiation Fibrotic Responses in Prostate Stroma via N6-Methyladenosine Modification of LOX

November 20, 2025

[International Journal of Radiation Oncology Biology Physics] Dietary α-ketoglutarate supplementation may serve as a mechanism-based strategy to alleviate radiation toxicity in patients with prostate cancer, offering a potential therapeutic pathway to improve treatment outcomes.

GLP1 Receptor Agonism Alters Growth and Therapeutic Response in Prostate Cancer

November 20, 2025

[Endocrine-Related Cancer] In prostate cancer models, semaglutide decreased cell proliferation, glycolytic function, and phospho-kinase-mediated signaling.

Osteocytes Under Mechanical Loading Regulate PC-3 Cancer Cell-Mineral Interactions during Early-Stage Metastasis to Bone

November 20, 2025

[Advanced Biology] The inhibitory role of mechanical loading of osteocytes on the early-stage metastasis of the endosteal surface during prostate cancer bone metastasis was demonstrated.

Therapy-Induced Senescence in Prostate Cancer: Mechanisms, Therapeutic Strategies, and Clinical Implications

November 20, 2025

[Gene] The authors explore the molecular mechanisms of senescence, the diverse therapeutic strategies that induce it, and the dual roles it plays in prostate cancer progression and treatment resistance.

Curium Announces First Commercial Doses of Diagnostic Radiopharmaceutical in Czech Republic and Slovakia for Patients with Prostate Cancer

November 20, 2025

[Curium] Curium announced that patients in the Czech Republic and Slovakia received the first doses of diagnostic radiopharmaceuticals used to indicate the detection of prostate-specific membrane antigen-positive lesions with positron emission tomography in patients with prostate cancer.

Published since 2010, Prostate Cell News compiles top scientific journal articles covering the characterization, behavior, and culturing of prostate cells. Additionally, our editorial team curates the latest press releases, technical advances, jobs, and events relevant to the prostate cell research community. Prostate Cell News saves scientists valuable time while keeping them informed in their field, facilitating the rapid exchange of cutting edge research updates and science news.