Prostate Cell News
Prostate Cell News is an online resource summarizing the latest prostate cell research.
Mitochondrial SLC25A10 Promotes Prostate Cancer Progression by Inhibiting Ferritinophagy
[Cell Death Discovery] Investigators systematically analyzed transcriptomic data from The Cancer Genome Atlas and performed Venn analysis to identify genes associated with prostate cancer progression.
Characterization of RNA Editing Gene APOBEC3C As a Candidate Tumor Suppressor in Prostate Cancer
[Scientific Reports] Researchers evaluated RNA-editing genes in prostate cancer (PCa). Notably, the APOBEC3 genes are clustered in terms of their chromosomal locations, and their transcriptional changes exhibit significant positive correlations in both primary PCa and castration-resistant prostate cancer
Significance of Androgen Receptor and Its Potential for Anti-Androgen/Androgen Receptor-Antagonist Therapy in Ovarian Cancers
[PLOS One] Researchers evaluated androgen receptor expression among different types of ovarian cancers and compared the results to estrogen and progesterone receptors.
Therapeutic Efficacy of Melatonin and Flutamide Combination in Safety for Prostate Cancer: An In Vitro Study
[DNA and Cell Biology] Investigators evaluated the effect of melatonin, flutamide, and melatonin–flutamide combination therapy in LNCaP, DU145, and PC3 cell lines.
Targeting PCNA/AR Interaction Inhibits AR-Mediated Signaling in Castration Resistant Prostate Cancer Cells
[Oncotarget] Scientists identified a second PIP-box in the DNA binding domain of androgen receptor (AR) and found that dihydrotestosterone enhances the binding of full-length AR but not a constitutively active variant to proliferating cell nuclear antigen (PCNA).
Dysregulation of AR and ERα Caused Ovarian Alterations in Gerbils Prenatally Exposed to 17α-ethinylestradiol and Pequi Oil
[Histochemistry and Cell Biology] Scientists investigated the effects of prenatal exposure to pequi oil and 17α-ethinylestradiol (EE2) on the histomorphometry and receptor expression (androgen receptor (AR) and estrogen receptor alpha (ERα) in gerbil ovaries (Meriones unguiculatus) during aging.
Synergistic Targeting Strategies for Prostate Cancer
[Nature Reviews Urology] Immunotherapy, targeted therapy and gene therapy could have reciprocal synergistic effects in prostate cancer in combination, resulting in a proposed synergistic model encompassing these three therapeutic modalities, presenting novel potential treatment strategies for prostate cancer.
Prostate Cancer Foundation Provides Over $16 Million to Fund Innovative Prostate Cancer Research Through Annual Challenge Awards Program
[The Prostate Cancer Foundation] The Prostate Cancer Foundation announced the recipients of its 2024 Challenge Awards, funding over $16 million in innovative prostate cancer research for cross-disciplinary, multi-institutional teams of investigators.
The Anti-Diabetic PPARγ Agonist Pioglitazone Inhibits Cell Proliferation and Induces Metabolic Reprogramming in Prostate Cancer
[Molecular Cancer] The authors suggested that Pioglitazone reduces prostate cancer (PCa) cell proliferation and induces metabolic and epithelial changes, highlighting the potential of repurposing metabolic drugs for PCa therapy.
CASK Promotes Prostate Cancer Progression via Kinase-Dependent Activation of AKT
[International Journal of Biological Macromolecules] Researchers investigated the roles of calcium/calmodulin-dependent serine protein kinase in prostate cancer (PCa) progression, cell migration, and invasion. They found that CASK is up-regulated in PCa tissues of patients.
The PPARβ/CERK/C1P Signaling Pathway Is a Potential Mechanism by Which Antimony Exposure Promotes Prostate Cancer Cell Proliferation
[Ecotoxicology and Environmental Safety] To explore the relationship between antimony exposure and cell proliferation, scientists found that the level of ceramide-1-phosphate (C1P), one of the metabolites of ceramide, increased after antimony exposure, and C1P can promote the proliferation of prostate cancer cells and antagonize the apoptosis induced by ceramide.
Insights into the Cellular Lipid Cascade of Prostate Cells Explored Using Infrared Microspectroscopy
[Analyst] Fourier transform infrared imaging coupled with fluorescence microscopy was used to follow arachidonic acid metabolism in prostate cancer cell lines.
Published since 2010, Prostate Cell News compiles top scientific journal articles covering the characterization, behavior, and culturing of prostate cells. Additionally, our editorial team curates the latest press releases, technical advances, jobs, and events relevant to the prostate cell research community. Prostate Cell News saves scientists valuable time while keeping them informed in their field, facilitating the rapid exchange of cutting edge research updates and science news.