[Nature Immunology] Scientists generated hepatitis B virus-specific CD4⁺ T cell receptor transgenic mice to show that CD4⁺ effector T cells can prevent and reverse the CD8⁺ T cell dysfunction induced by hepatocellular priming.

[Nature Microbiology] Researchers identified a distinct glycoprotein H complex that is abundant on human cytomegalovirus virions and enhances infection of endothelial cells.

[Nature Communications] siRNA screening identified Rab27a as a critical host factor regulating the transport of influenza A virus membrane proteins to the cell surface.

[Proceedings of the National Academy of Sciences of the United States of America] Researchers provided insights into how cells navigate the balance between survival and immune defense during herpes simplex virus 1 infection, offering conceptual advancements that may extend to other viral infections.

[Journal of Infectious Diseases] Influenza strain–specific cellular responses were detectable following vaccination despite expected B-cell depletion in patients receiving active treatment for hematological malignancy.

[PLoS Pathogens] Scientists uncovered neogenin, a member of the immunoglobulin superfamily expressed in primary human airway cultures, as a potential epsin 1 interactor and virus receptor candidate.

[Scientific Reports] Investigators identified compounds that inhibit an interaction between large hepatitis B surface and hepatitis B core proteins, which are considered to be important for HBV envelope formation.

[Nature Communications] Investigators identified vesicle-associated membrane protein 5 as a potent cell-autonomous defense factor against coronaviruses, including SARS-CoV-2, with high expression levels observed in embryonic stem cells and mesoderm.

[Microbiology Spectrum] Investigators suggested that multiple domains of Nsp3, particularly Ubl1 and Y, shepherd the 5’ UTR of the viral genome during translocation through the DMV membrane, priming the Ubl1 domain to load the genome onto N protein.

[Inflammatory Bowel Diseases] Investigators described outcomes among those who developed SARS-CoV-2 infection following vaccination, characterize SARS-CoV-2 antibodies 1 year post-vaccination, and identify factors associated with durable serologic response.

[Scientific Reports] Researchers compared immune responses elicited by intramuscular mRNA vaccination alone with those elicited by intramuscular mRNA vaccination followed by intranasal administration of ChAdOx1 nCoV-19 vaccine in mice.

[Inflammopharmacology] Researchers examine the epidemiology, risk factors, and clinical manifestations of long COVID, with a focus on its impact on cardiopulmonary, neurological, and mental health.