Liver Cell Created From Subcutaneous Fat
A team of doctors has succeeded in creating a hepatic cell out of subcutaneous fat, a development that might lead to a regenerative medicine technique that would enable patients with hepatitis or cirrhosis to have their livers repaired.
Article
Researchers Report Alternative Stem Cell Source in Amniotic Fluid
Researchers at Wake Forest and Harvard report they have drawn stem cells from amniotic fluid donated by pregnant women. They say those cells were successfully turned into several different tissue cell types, including brain, liver and bone.
Article
Scientists Discover Stage at Which an Embryonic Cell is Fated to Become a Stem Cell
Cambridge scientists have discovered the stage at which some of the cells of a fertilised mammalian egg are fated to develop into stem cells and why this occurs.
Article
Modified Skin Cells Resist Bugs
US scientists say they have made germ-resistant skin that could one day save the lives of severe burns victims.
Article
University of Southern California Study Supports a Stem Cell Origin of Cancer
According to the study’s findings, genes that are reversibly repressed in embryonic stem cells are over-represented among genes that are permanently silenced in cancers; this link lends support to the increasingly discussed theory that cancer is rooted in small populations of stem cells.
Article
Cell Therapy For Parkinson’s
To directly combat the decline in dopamine levels associated with Parkinson’s, researchers at the company NeuroProgen have developed a new drug on the basis of stem cells which is now being adapted to the regulatory standards of the pharmaceutical industry in partnership with the Fraunhofer Institute for Cell Therapy and Immunology IZI.
Article
Dramatic Results from Combo Therapy Surprises Krabbé-disease Researchers
A combination of bone marrow transplantation and gene therapy greatly lengthened the lives of laboratory mice doomed by a rapidly progressing, fatal neurodegenerative disorder also found in people.
Article
Pluristem Submits Pre-Investigational New Drug Document to FDA
An innovative adjuvant cell therapy product based on PLacenta eXpanded Mesenchymal cells, PLX- I is expected to be used to improve the engraftment of Umbilical Cord Blood when treating blood cancer and blood disorders. Approval of the Pre-IND document by the FDA precedes initiation of Phase I trials.
Article
Stem-cell Hope Put on Hold by US Regulator
ReNeuron recently suffered a setback when a US regulator put the group’s first clinical trial on hold.
Article
Takara Bio Obtains Clinical Trial Approval of Gene Therapy Treatment for Chronic Granulomatosis
Bio affiliate ViroMed Co., Ltd., based in Korea, announced the Korea Food & Drug Administration approval of their clinical trial of VM106, gene therapy treatment drug, for chronic granulomatosis.
Article
Ark Therapeutics Holds Positive End Of Phase II Meeting With FDA On Trinam(R) Gene Therapy
Ark Therapeutics Group plc has announced that it has held a positive “end of Phase II” meeting with the US Food and Drug Administration regarding Trinam(R), its novel gene therapy to prevent blood vessels blocking in kidney dialysis patients who have undergone vascular access graft surgery.
Article
Stem Cell Device Could Have Role in Cancer Treatment
Researchers at the University of Rochester and StemCapture have unveiled a new device technology that makes it possible to harvest stem cells from the blood, bypassing the controversial use of stem cells sourced from embryos.
Article
Womb Transplants May One Day Be a Reality
Current organ donor networks appear able to supply human wombs, or uteruses, for transplantation as a possible approach to treating infertility.
Article
Odds Favor Hawaiian’s Return to Health with Stem Cell Therapy
Placed beyond hope by medical professionals in his own country, a US man takes his chances with adult stem therapy to treat his heart disease.
Article
ABSTRACT, REVIEWS AND SPECIAL REPORTS
Haematopoietic Stem Cell Transplantation Trends in Children Over the Last Three Decades: A Survey By the Paediatric Diseases Working Party of the European Group for Blood and Marrow Transplantation
This paper describes the trends in haematopoietic stem cell transplantation (HSCT) activity for children in Europe over the last three decades. It shows that indications for paediatric HSCT have changed considerably during the last seven years and that these changes provide tools for decision making in health-care planning and counselling.
Article
Efficient Non-Viral Ocular Gene Transfer with Compacted DNA Nanoparticles
This article discusses a treatment strategy that appears to be clinically viable and provides a highly efficient non-viral technology to safely deliver and express nucleic acids in the retina and other ocular tissues.
Article