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Justin.choi
Umbilical & Placental Cell News
Large-Scale Analysis of MicroRNA Expression in Motor Neuron-Like Cells Derived from Human Umbilical Cord Blood Mesenchymal Stem Cells
[Scientific Reports] Human CB-MSCs were isolated and characterized using flow cytometry. Cell differentiation has been induced by combining retinoic acid and sonic hedgehog in a two-step protocol for 14 days.
Umbilical & Placental Cell News
Human Placental Development and Function
[Seminars in Cell & Developmental Biology] Scientists examine current knowledge of early human placental development, discuss the critical role of the maternal endometrium and of the fetal-maternal dialogue in pregnancy success, and they explore the latest models of trophoblast and endometrial stem cells.
Umbilical & Placental Cell News
Essent Biologics Launches Human Mesenchymal Stem Cells for Regenerative Medicine, Biopharmaceutical and Cell Therapy Research
[Essent Biologicsâ„¢ (PR NewsWire, Inc.)] Essent Biologicsâ„¢ announced the launch of its human mesenchymal stem cells for regenerative medicine, biopharmaceutical and cell therapy research.
Mammary Cell News
H3K27me3 Conditions Chemotolerance in Triple-Negative Breast Cancer
[Nature Genetics] By monitoring epigenomes, transcriptomes and lineages with single-cell resolution, scientists showed that the repressive histone mark trimethylation of histone H3 at lysine 27 (H3K27me3) regulated cell fate at the onset of chemotherapy.
Mammary Cell News
Progesterone Activates GPR126 to Promote Breast Cancer Development via the Gi Pathway
[Proceedings of the National Academy of Sciences of the United States of America] Scientists identified a membrane receptor for progesterone/17-hydroxyprogesterone and delineated the mechanisms by which GPR126 participated in potential tumor progression in TNBC.
Mammary Cell News
LINC00355 Regulates p27KIP Expression by Binding to MENIN to Induce Proliferation in Late-Stage Relapse Breast Cancer
[npj Breast Cancer] Researchers identified 1127 lncRNAs differentially expressed in late-stage relapse (LSR) breast cancer (BC) via transcriptome sequencing and analysis of 72 early-stage and 24 LSR BC patient tumors.
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CAR T or NK Cells Targeting Mismatched HLA-DR Molecules in Acute Myeloid Leukemia after Allogeneic Hematopoietic Stem Cell Transplant
[Nature Cancer] Investigators identified KG2032 as a monoclonal antibody specifically bound to acute myeloid leukemia cells in about half of patients, but not to normal leukocytes other than B lymphocytes.
Intranasal Prime-Boost RNA Vaccination Elicits Potent T Cell Response for Lung Cancer Therapy
[Signal Transduction and Targeted Therapy] Researchers developed a non-invasive intranasal cancer vaccine utilizing circular RNA encapsulated in lipid nanoparticles to induce localized mucosal immune responses.
Lupus Research Alliance Grants Inaugural Awards to 11 Researchers Focused on Engineered Cell Therapies for Lupus
[Lupus Research Alliance] The Lupus Research Alliance announced the inaugural recipients of the new Targeted Research Program on Engineered Cell Therapies for Lupus (TRP-ECT) to support the development and mechanistic understanding of safe and accessible next-generation engineered cell therapies for people with lupus.
