CiRA and Takeda Enter Ten-Year Collaboration on iPS Cell Research Center for iPS Cell Research Application (CiRA) of Kyoto University and Takeda Pharmaceutical Company Limited announced that they will work together to develop clinical applications of induced pluripotent stem cells in areas such as heart failure, diabetes mellitus, neurological disorders and cancer immunotherapy. [Takeda Pharmaceutical Company Limited.] Press Release REGiMMUNE Announces Collaboration with JDRF and Pfizer Inc. for Type 1 Diabetes Prevention and Treatment Promoting Regulatory T-Cells REGiMMUNE Corporation and JDRF announced a partnership, along with financial assistance and scientific expertise from Pfizer Inc., for a research collaboration to develop an antigen-specific immunotherapy utilizing RGI’s proprietary αGalCer/liposome platform for immunological tolerance for the treatment of type 1 diabetes. [REGiMMUNE Corporation] Press Release Argos Therapeutics Licenses Arcelis® Technology Platform to Lummy HK for Development of Personalized Immunotherapies to Treat Cancer in China Argos Therapeutics, Inc., a biopharmaceutical company focused on the development and commercialization of fully personalized immunotherapies for the treatment of cancer based on the Arcelis® technology platform, and Lummy (Hong Kong) Co. Ltd. announced they have entered into a license agreement. [Argos Therapeutics, Inc.] Press Release CheckMate-057, a Pivotal Phase III Opdivo (Nivolumab) Lung Cancer Trial, Stopped Early Bristol-Myers Squibb Company announced that an open-label, randomized Phase III study evaluating Opdivo versus docetaxel in previously treated patients with advanced non-squamous non-small cell lung cancer was stopped early because an assessment conducted by the independent data monitoring committee concluded that the study met its endpoint, demonstrating superior overall survival in patients receiving Opdivo compared to the control arm. [Bristol-Myers Squibb Company] Press Release Athersys Announces Results from Phase II Study of MultiStem® Cell Therapy for Treatment of Ischemic Stroke Athersys, Inc. announced interim results from its exploratory Phase II clinical study of the intravenous administration of MultiStem® cell therapy to treat patients who have suffered an ischemic stroke. With respect to the primary and secondary endpoints, the cell therapy did not show a difference at 90 days compared to placebo. [Athersys, Inc.] Press Release AstraZeneca Announces Updated Progression Free Survival Data for Investigational Non-Small Cell Lung Cancer Medicine AZD9291 AstraZeneca announced latest data from the ongoing AURA study of AZD9291 in patients with advanced epidermal growth factor receptor mutation positive non-small cell lung cancer, who also have the T790M resistance mutation. [AstraZeneca] Press Release ReNeuron Files Application to Commence Phase I/II Clinical Trial in the US with Its Stem Cell Therapy Candidate for the Blindness-Causing Disease, Retinitis Pigmentosa ReNeuron Group plc announced that it has filed an investigational new drug application with the US FDA to commence a Phase I/II clinical trial with its human retinal progenitor cell therapy candidate for retinitis pigmentosa. [ReNeuron Group plc] Press Release Isarna Initiates First-in-Human Phase I Trial for ISTH0036 to Treat Advanced Glaucoma Isarna Therapeutics announced the initiation of a Phase I clinical trial with ISTH0036, an antisense oligonucleotide selectively targeting transforming growth factor beta to treat advanced glaucoma. [Isarna Therapeutics] Press Release RepliCel Life Sciences Receives Approval to Conduct Clinical Trial for Patients with Chronic Achilles Tendinosis RepliCel Life Sciences Inc. announced that it has received approval from the University of British Columbia Clinical Research Ethics Board to conduct a Phase I/II clinical trial at the UBC Hospital. The trial will investigate the potential of RepliCel’s tendon repair product, RCT-01, to treat chronic tendon injury. [RepliCel Life Sciences Inc.] Press Release |