| PUBLICATIONS (Ranked by Impact Factor of the Journal) | p57Kip2 and p27Kip1 Cooperate to Maintain Hematopoietic Stem Cell Quiescence through Interactions with Heat Shock Cognate Protein 70 In this study, investigators report that cell cycle entry proceeded normally in hematopoietic stem cells null for cyclin-dependent kinase inhibitor p57 due to compensatory upregulation of p27. [Cell Stem Cell] Abstract p57 Is Required for Quiescence and Maintenance of Adult Hematopoietic Stem Cells Results suggest that, among Cip/Kip family cyclin-dependent kinase inhibitors, p57 plays a predominant role in the quiescence and maintenance of adult hematopoietic stem cells. [Cell Stem Cell] Abstract Cooperation Between Both Wnt/β-Catenin and PTEN/PI3K/Akt Signaling Promotes Primitive Hematopoietic Stem Cell Self-Renewal and Expansion Using a hematopoietic stem and progenitor cell-specific conditional induction line, researchers generated a compound genetic model bearing both Pten deletion and β-catenin activation. [Genes Dev] Abstract Differential Effects of HOXB4 and NUP98-HOXA10hd on Hematopoietic Repopulating Cells in a Nonhuman Primate Model Researchers show that HOXB4 and NUP98-HOXA10hd (NA10hd) both have a significant impact on hematopoietic reconstitution; however, these effects are differential and therefore may offer complementary strategies for hematopoietic stem cell expansion. [Hum Gene Ther] Abstract Manipulation of Oxygenation and Flow-Induced Shear Stress Can Increase the In Vitro Yield of Platelets from Cord Blood Using CD34 positively selected cord blood cells, researchers investigated ways to increase platelet quality and yield in a three-dimensional modular perfusion bioreactor system. [Tissue Eng Part C Methods] Abstract Priming of Mesenchymal Stem Cells with Oxytocin Enhances the Cardiac Repair in Ischemia/Reperfusion Injury In this study, umbilical cord blood-derived mesenchymal stem cells were cultured with oxytocin and examined for their therapeutic effect in an infarcted heart. [Cells Tissues Organs] Abstract Lethal Human Herpesvirus-6 Encephalitis After Cord Blood Transplant Clinical, biological, pathological, and imaging findings were all suggestive of lethal human herpesvirus-6-associated encephalitis in a 61-year-old man who had undergone a cord blood transplant. [Transpl Infect Dis] Abstract Effect of Human Cytomegalovirus Infection on the Expression of Hoxb2 and Hoxb4 Genes in the Developmental Process of Cord Blood Erythroid Progenitors The aim of the study was to investigate the role of Hoxb2 and Hoxb4 gene expression induced by human cytomegalovirus and/or all-trans retinoic acid on the proliferation and committed differentiation process of human cord blood hematopoietic stem cells to colony-forming erythroid progenitor cells in vitro. [Mol Med Rep] Abstract |
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