Bronchoalveolar Lavage and Lung Biopsy in Patients with Cancer and Hematopoietic Stem-Cell Transplantation Recipients: A Systematic Review and Meta-Analysis Investigators describe the diagnostic yield and complication rate of bronchoalveolar lavage and lung biopsy in the evaluation of pulmonary lesions in patients with cancer and recipients of hematopoietic stem-cell transplantation. [J Clin Oncol] Abstract Allogeneic Stem-Cell Transplantation in Patients with NPM1-Mutated Acute Myeloid Leukemia: Results from a Prospective Donor versus No-Donor Analysis of Patients after Upfront HLA Typing within the SAL-AML 2003 Trial The authors assessed the predictive value with regard to allogeneic stem-cell transplantation (SCT), they compared the clinical course of patients with mutated nucleophosmin-1 (NPM1) gene acute myeloid leukemia (AML) eligible for allogeneic SCT in a donor versus no-donor analysis. [J Clin Oncol] Abstract Optimal Method for Collection of Umbilical Cord Blood: An Egyptian Trial for a Public Cord Blood Bank Investigators evaluated the effect of the method of collection of umbilical cord blood on the yield of the cord blood units. They found that in utero collection gave significantly larger volumes of cord blood and higher total nucleated cell counts than ex utero collection. [Transfusion] Abstract Human Mesenchymal Stem Cells as a Novel Platform for Simultaneous Evaluation of Cytotoxicity and Genotoxicity of Pharmaceuticals The authors grew umbilical cord mesenchymal stem cells (UC-MSCs) on coverslips eliminating the cumbersome technique involving hypotonic treatment, fixation and preparing smears required for suspension culture. They inspected the cytotoxic and genotoxic effects of two known mutagens, mitomycin-C and hydrogen peroxide, on UC-MSCs, lymphocytes and A549 cells. [Mutagenesis] Abstract Use of Allogeneic Stem Cell Transplantation for Moderate-Severe Glanzmann Thrombasthenia Researchers report the case of an eight-month-old girl diagnosed with moderate-severe Glanzmann thrombasthenia, who was successfully treated with a reduced-intensity, human leukocyte antigen-identical allogeneic stem cell transplantation. [Platelets] Abstract Prevalence and Clinical Significance of Potential Drug-Drug Interaction in Hematopoietic Stem Cell Transplantation Investigators performed a cross-sectional study based on the evaluation of prescriptions to hematopoietic stem cell transplantation patients on the day of infusion. The potential drug-drug interactions were analyzed using the DRUG-REAX® system and classified according to the severity level, available scientific evidence, time of onset, and potential clinical impact. [Cancer Chemother Pharmacol] Abstract Hematopoietic Stem Cell Transplantation for Treatment of Primary CNS Lymphoma: Single Center Experience and Literature Review Researchers report our single center experience with five primary central nervous system (CNS) lymphoma patients, who had achieved an objective response after a high-dose methotrexate based induction therapy and consecutively received a high-dose chemotherapy, consisting of carmustine and thiotepa, followed by autologous hematopoietic stem cell transplantation. [Eur J Haematol] Abstract Patterns of Monocyte Subpopulations and Their Surface Expression of HLA-DR during Adverse Events after Hematopoietic Stem Cell Transplantation Scientists describe the monocyte subpopulations and their human leukocyte antigen DR expression during the post-transplant period as well as during transplant-related adverse events of 30 pediatric patients and young adults with hemato-oncological malignancies and immunodeficiency disorders in comparison to healthy children and young adults. [Ann Hematol] Abstract |