Propagation of Pure Fetal and Maternal Mesenchymal Stromal Cells from Terminal Chorionic Villi of Human Term Placenta Scientists demonstrated the presence of fetal and maternal cells within the tips of terminal chorionic villi of normal human term placenta, and they exploited inherent differences in the adhesive and migratory properties of maternal versus fetal cells, to establish pure mesenchymal stromal cell cultures of both cell types. [Sci Rep] Full Article Involvement of Immune Responses in the Efficacy of Cord Blood Cell Therapy for Cerebral Palsy The authors evaluated the efficacy of umbilical cord blood cell for patients with cerebral palsy in a randomized, placebo-controlled, double-blind trial and also assessed factors and mechanisms related to the efficacy. [Stem Cells Dev] Abstract Direct Conversion of Cord Blood CD34+ Cells into Neural Stem Cells by OCT4 Researchers report a method to generate neural stem cells from cord blood CD34-positive cells by ectopic expression of OCT4 in a feeder-free system. [Stem Cells Transl Med] Abstract Effect of Human Umbilical Cord Blood Derived Lineage Negative Stem Cells Transplanted in Amyloid-β Induced Cognitive Impaired Mice The authors examined the therapeutic efficacy of human umbilical cord blood derived lineage negative stem cells in alleviating behavioral and neuropathological deficits in a mouse model of cognitive impairment induced by bilateral intrahippocampal injection of amyloid-β. [Behav Brain Res] Abstract Effect of Granulocyte Colony-Stimulating Factor Combined Conditioning in Cord Blood Transplantation for Myelodysplastic Syndrome and Secondary Acute Myeloid Leukemia: A Retrospective Study in Japan Scientists conducted a retrospective nationwide study of 336 adult patients with myelodysplastic syndrome and secondary acute myeloid leukemia after single-unit cord blood transplantation. [Biol Blood Marrow Transplant] Abstract The Use of Human Amniotic Fluid Stem Cells as an Adjunct to Promote Pulmonary Development in a Rabbit Model for Congenital Diaphragmatic Hernia The authors evaluated the potential benefit of intra-tracheal injection of human amniotic fluid stem cells on pulmonary development combined with TO in a rabbit model for congenital diaphragmatic hernia. [Prenat Diagn] Abstract Ex Vivo and In Vivo Modulatory Effects of Umbilical Cord Wharton’s Jelly Stem Cells on Human Oral Mucosa Stroma Substitutes Researchers generated human oral mucosa substitutes with oral mucosa keratinocytes and human umbilical cord Wharton’s jelly stem cells to determine the influence of these cell sources on stromal differentiation. [Histol Histopathol] Abstract | Full Article In Vitro Generation of Functional Dendritic Cells Differentiated from CD34 Negative Cells Isolated from Human Umbilical Cord Blood Scientists used CD34 antibody to isolate CD34+ and CD34− cells and compared the ability to differentiate into dendritic cells. They used a two-step method combined with the magnetic bead sorting system to isolate CD34+ and CD34− cells from human umbilical cord blood. [Cell Biol Int] Abstract |